80th anniversary logo
Welcome to Southeast Missouri Hospital

Since its founding in 1928 as a small, 72-bed community hospital, Southeast Missouri Hospital has grown to a highly respected 269-bed regional medical complex serving over 573,000 people in 20 counties of southeast Missouri and southern Illinois. 

Our mailing address is: 1701 Lacey Street, Cape Girardeau, MO 63701

Our main phone number is: 573-334-4822. Click here for other phone numbers

Southeast's specialized centers of care include 

The Regional Heart Center

Regional Cancer Center

Regional Brain and Spine Center

Women's and Children's Center

Emergency Services

Orthopedics and Joint Replacement Center

Southeast Missouri Hospital overlooks Capaha Lake
Each year, tens of thousands of patients see the difference at Southeast in technology, services and care. Welcome.

Southeast Missouri Hospital is a proud provider in a number of insurance networks.
Check our current listing.